Telecommuting may be an option worth looking into, whether as your only position or as a combination of working at home and working at the office with your current employer.
For those who are trying to work out a flexible schedule in your current job, the key is to assure your boss that not only can you get as much work done, but can be even more productive from home on that day or those days you telecommute. Your reasons may be numerous, ranging from saving a day of commuting or for child-care reasons.
You may offer to attempt working one day a week from home on a trial basis. If you are given this opportunity, you can open the door to future telecommuting days, planned or unplanned (based on a need that arises in your personal life), by producing an increased quantity over what you or a typical employee does on a typical workday in the office.
For those seeking to work completely at home, there are several web sites available offering specific work opportunities. Many of these are part-time or on a freelancing basis, but this is a great chance to enhance your resume and build for future opportunities.
If you have done any work at home from any job or any freelancing, make sure to highlight that fact on your resume, stressing that you worked successfully off-site or via telecommunication. As with any type of job, a potential employer wants to see experience, which in this case is not limited to what you have done, but also includes where you have done it.